The Ultimate Guide to Azelaic Acid: Benefits, Uses, and Top Products for Clear Skin

If you’ve struggled with acne, you’re likely familiar with common treatments like benzoyl peroxide and salicylic acid. However, these options can often be harsh on sensitive skin. Enter azelaic acid, a lesser-known yet powerful ingredient that effectively treats and prevents acne while being gentler on the skin. Dr. Rachel Westbay, a board-certified dermatologist, highlights its ability to unclog pores, fade dark spots, and reduce acne scars.

What is Azelaic Acid?

Azelaic acid is a naturally occurring compound that acts as a tyrosinase inhibitor—this means it prevents the enzyme responsible for melanin production, effectively evening out skin tone. It’s particularly beneficial for those dealing with hyperpigmentation from conditions like melasma and helps lighten acne scars.

How Does Azelaic Acid Work?

• Antibacterial Properties: Targets the bacteria that contribute to acne.
• Antioxidant Effects: Reduces oxidative stress and inflammation.
• Mildness: Less irritating than other acne treatments, making it ideal for sensitive skin.

Dr. Lindsey Bordone from Columbia University Medical Center notes that azelaic acid is also one of the few pregnancy-safe acne treatments available.

Choosing the Right Azelaic Acid Products

While prescription options typically boast higher concentrations (15% to 20%), over-the-counter products often contain up to 10% azelaic acid. To ensure effectiveness, experts recommend:

Key Considerations:

• Concentration: Higher concentration generally means better results.
• Formulation: Azelaic acid is found in creams, gels, serums, cleansers, and masks. Choose based on your routine and skin type.
• Additional Ingredients: Pair azelaic acid with skin-brightening assets like niacinamide or vitamin C, but avoid combining it with harsher acids (e.g., AHAs and BHAs) to prevent irritation.

Top Azelaic Acid Products for 2025

Here’s a curated list of some of the best azelaic acid products based on expert recommendations:

1. Best Overall: The Ordinary Azelaic Acid 10% Suspension Brightening Cream

• Type: Cream
• Concentration: 10%
• Pros: Affordable, Safe for sensitive skin, Effective in reducing dark spots.
• Check it out here.

2. Best for Dark Spots: Paula’s Choice 10% Azelaic Acid Booster

• Type: Serum
• Concentration: 10%
• Pros: Evens skin tone, Prevents breakouts, Fragrance-free.
• Explore more here.

3. Best for Scars: Topicals Faded Brightening and Clearing Serum

• Type: Serum
• Concentration: N/A
• Pros: Quick results, Focused on hyperpigmentation.
• Find it here.

4. Best with Vitamin C: Naturium Azelaic Topical Acid 10%

• Type: Serum
• Concentration: 10%
• Pros: Balances oil, Hydrating, Vitamin C boost.
• Learn more here.

5. Best for Irritated Skin: Peach Slices Redness Relief Azelaic Acid Serum

• Type: Serum
• Concentration: 10%
• Pros: Hydrating, Reduces redness, Suitable for acne-prone skin.
• Discover it here.

Frequently Asked Questions

Who Should Use Azelaic Acid?

Azelaic acid is suitable for:

• Those with sensitive skin.
• Pregnant or breastfeeding women.
• Individuals in their early teens.

However, it may irritate very sensitive skin or be less effective for severe cystic acne.

How Often Can You Use Azelaic Acid?

Start with once daily use. If well-tolerated, increase to twice a day, complemented by a gentle cleanser and a good moisturizer with SPF.

What Percentage is Most Effective?

Experts recommend:

• Prescription: 15%-20% for best results.
• OTC: Up to 10%, but ideally combined with other products for effectiveness.

What Can You Layer with Azelaic Acid?

Consider pairing it with:

• Niacinamide: Natural anti-inflammatory.
• Hyaluronic Acid: For moisture retention.

Avoid mixing with salicylic acid and glycolic acid to prevent irritation.

Conclusion

Azelaic acid presents a gentle yet effective solution for acne-prone and sensitive skin. By choosing the right products and incorporating this powerful ingredient into your skincare routine, you can achieve clearer, brighter skin.

Discover More

For more insights on skincare treatments and product recommendations, explore expert resources and trusted brands.